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American Academy of Pediatrics
ENDOCRINOLOGY

Growing Numbers for Idiopathic Short Stature Growth Hormone Therapy

AAP Grand Rounds February 2007, 17 (2) 19-20; DOI: https://doi.org/10.1542/gr.17-2-19-a
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Source: Reiter EO, Price DA, Wilton P, et al. Effect of growth hormone (GH) treatment on the near-final height of 1258 patients with idiopathic GH deficiency: analysis of a large international database. J Clin Endocrinol Metab. 2006;91:2047–2054; doi:10.1210/jc.2005-2284OpenUrlCrossRefPubMed

These investigators from Baystate Children’s Hospital in Springfield, Mass; Manchester, UK; Gothenburg, Sweden; and Tubingen, Germany conducted an analysis of data from 1,258 children with growth hormone deficiency to determine how final adult height compared with midparental height. The data were abstracted from the Pfizer International Growth Database, also known as KIGS. Of the 1,258 patients evaluated, 980 were of multinational Caucasian origin and 278 were of Japanese origin. There were 747 children with a diagnosis of isolated growth hormone deficiency (IGHD); the remaining 511 had a diagnosis of multiple pituitary hormone deficiency (MPHD). Children were treated for at least 4 years and had at least 1 …

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AAP Grand Rounds
Vol. 17, Issue 2
1 Feb 2007
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Growing Numbers for Idiopathic Short Stature Growth Hormone Therapy
AAP Grand Rounds Feb 2007, 17 (2) 19-20; DOI: 10.1542/gr.17-2-19-a

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Growing Numbers for Idiopathic Short Stature Growth Hormone Therapy
AAP Grand Rounds Feb 2007, 17 (2) 19-20; DOI: 10.1542/gr.17-2-19-a
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