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Children treated with long-term glucocorticoid therapy are at risk for slowing of linear growth and decreased bone and muscle mass. Researchers from the Robert Debre Teaching Hospital in Paris, France, enrolled 30 glucocorticoid-dependent children with juvenile idiopathic arthritis (JIA) into a randomized, controlled three-year trial to determine the impact of recombinant growth hormone (rhGH) on linear growth preservation, body composition, and bone mineralization. All patients were prepubertal at the start of the study and had been on prednisone therapy, 0.2 mg/kg or greater per …
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