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Because the effects of maternal multivitamin supplementation on the risk of malaria in children are unknown,1,3,4 researchers from Boston, Mass; Munich, Germany; and Dar es Salaam, Tanzania, sought to learn the impact of providing multivitamins or vitamin A/β-carotene (VA/BC) supplements during pregnancy and lactation to HIV-infected women on their children’s risk of malaria in the first two years of life.
A total of 1,078 HIV-infected pregnant women participated in this community-based, prospective, randomized, double-blind, placebo-controlled trial in Dar es Salaam. Antiretroviral therapy was unavailable at the time of the study. Women were randomized into one of four treatment arms: 1) multivitamins; 2) VA/ BC; 3) multivitamins and VA/BC; …
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