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PICO
Question: Among healthy children, does substitution of organic foods for conventionally grown foods in the diet result in lower urinary excretion of organophosphate pesticide metabolites?
Question Type: Intervention
Study Design: Prospective cohort study
Investigators from Emory University in Atlanta, GA, and the National Center for Environmental Health at the CDC compared exposure to organophosphorus (OP) pesticides in children when consuming a conventional diet or switching to an organic diet (pesticide-free).
Parents of study participants completed daily food diaries and collected their child’s urine twice daily during each of four sampling periods lasting approximately two weeks over the course of a year-long study period. Urine samples were screened for metabolites of five OP pesticides: malathion, chloropyrifos, diazinon, coumaphos, and methyl pirimiphos.
During two five-day stretches in the summer and fall sampling periods, the children’s conventional diets were replaced with organically grown fruits and vegetables, juices, and some wheat and corn-based items like pasta, cereal, popcorn, and chips. Meats, seafood, and dairy products rarely contain OP pesticides and were not substituted.
A total of 23 children (10 females, 13 males) ages 3 to 11 years old were enrolled, …
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