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PICO
Question:Among patients admitted to a pediatric hospital for non-oncology problems, can computerized surveillance programs identify adverse drug events?
Question type:Harm
Study design:Descriptive study
Investigators from St. Louis Children’s Hospital, St. Louis, MO (SLCH) performed a prospective evaluation of a rules-based computer surveillance program to detect inpatient adverse drug events (ADEs). The data monitored included patient-specific demographic, encounter, laboratory, and pharmacy information from hospital information systems for all admissions, excluding children with cancer, from February 1, 2008 to July 31, 2008.
The computer program generated alerts based on combinations of the knowledge-based rules and the patient-specific data. The rule set included modifications specific for pediatric settings plus rules for medication-induced electrolyte abnormalities such …
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