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PICO
Question: Among patients presenting to the emergency department with mild to moderate acute asthma, is post-stabilization outpatient therapy with montelukast as effective as prednisolone?
Question type: Treatment
Study design: Double-blind, randomized, non-inferiority trial
Investigators from the Hospital for Sick Children, University of Toronto in Toronto, Canada conducted a randomized, double-blind trial to determine the efficacy of using montelukast instead of prednisone/prednisolone in the outpatient stabilization of children following an episode of acute asthma. The study group consisted of a convenience sample of children 2 to 17 years …
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