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PICO
Question: Among children with autosomal dominant polycystic kidney disease diagnosed by prenatal ultrasound, what is the renal outcome as compared to children presenting with symptoms?
Question type: Prognosis
Study design: Retrospective record review
Investigators from Great Ormond Street Hospital for Children, London, conducted a retrospective study of children with autosomal dominant polycystic kidney disease (ADPKD) to compare the renal outcomes in children detected because of symptoms versus those discovered through family screening. Data on children who were referred with a clinical suspicion of ADPKD between 1987 and 2007 were reviewed.
Study patients included 31 children (17 male) who were asymptomatic and diagnosed by ultrasound screening …
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