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PICO
Question: Among breastfeeding mothers does DHA supplementation improve infant visual acuity and neuropsychological status at 5 years of age?
Question type: Intervention
Study design: Randomized controlled trial
Investigators from several United States institutions conducted a double-blinded randomized placebo-controlled trial to evaluate the long-term health benefits of supplementing lactating mothers with 200 mg per day of DHA (docosahexaenoic acid) during the first four months postpartum. Two hundred twenty-seven pregnant women who planned to breastfeed exclusively for at least four months were assigned randomly in a double-blinded fashion to receive one of two identical capsules daily for four months, starting within five days after delivery. One of the capsules contained 200 mg of DHA; the control contained a 50:50 mixture of soy and corn oils. The mothers were between 18 and 40 years of age, infant gestational age was greater than 37 …
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