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Question: Among children with a first-time seizure associated with an acute gastrointestinal illness, what is the prognosis and risk of recurrent seizures?
Question type: Prognosis
Study design: Prospective longitudinal cohort
Researchers at Seattle Children’s Research Institute and the Centers for Disease Control and Prevention (CDC) conducted a prospective longitudinal study to determine outcomes in children with first-time seizures associated with acute gastrointestinal illness. Patients aged 6 months through 6 years presenting to the emergency department with a first-time seizure were enrolled. Initial seizures were classified as febrile, nonfebrile-illness, or unprovoked; febrile and nonfebrile-illness seizures were further categorized as associated with acute gastroenteritis or acute nongastrointestinal illness. Stool samples were collected for viral studies and electroencephalograms (EEG) were obtained at the discretion of the treating physicians. Parents of children in …
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