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PICO
Question: Among children 1 to 24 months of age attending child care, what are the typical types of illnesses and frequency of parainfluenza type 4 virus?
Question type: Diagnosis
Study design: Prospective, longitudinal cohort
Investigators from Washington State prospectively assessed young children with respiratory illnesses attending child care centers, using polymerase chain reaction (PCR) to detect the viral etiology of each illness. The intent of the study was to determine the role of human parainfluenza virus type 4 (HPIV-4). All children 1 to 24 months of age, attending one of three large child care centers at least 20 hours per week during 35 of 41 months from February 2006 through June 2009, were recruited and followed for up to two years. Nasal specimens …
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