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PICO
Question: Among children with perforated appendicitis, is early appendectomy more cost-effective than delayed interval appendectomy?
Question type: Intervention
Study type: Randomized clinical trial
Investigators from the University of Tennessee conducted a randomized prospective trial to compare 2 management strategies for children with perforated appendicitis in order to determine which was most cost-effective. They had previously conducted a randomized prospective trial of early appendectomy (<24 hours after admission and following fluid resuscitation and antibiotics) versus initial medical management with delayed (interval) appendectomy 6 to 8 weeks after onset in 131 children.1 For the current study …
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