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PICO
Question: Among newborns of Staphylococcus aureus carrier and noncarrier mothers, what are the risk factors and route of S aureus transmission at birth and 1 month of age?
Question type: Causation
Study design: Cohort
Investigators at Sheba Medical Center in Tel Aviv, Israel conducted a prospective study to determine the rate and mode of transmission of Staphylococcus aureus from mothers to infants during the perinatal period and at 1 month of age. Maternal vaginal and nasal swabs were obtained at 3 time periods: on enrollment to the study at 34 to 40 weeks gestation, following delivery, and prior to discharge from the hospital. Carrier status was defined as a positive culture for S aureus at any time …
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