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Dawson and co-workers assessed the impact of H. influenzae b (Hib) vaccines on bacterial meningitis by examining the changes in the numbers of such infections from 1981–1995 at the Children’s Hospital and Regional Medical Center in Seattle, Washington. This retrospective chart review spanned the 5 years prior to Hib vaccines (1981–1985), 5 years during which unconjugated Hib polysaccharide vaccine was in use (1986–1990), and 5 years after the introduction of conjugate …
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