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PICO
Question: Among children with idiopathic toe-walking, does injecting botulinum toxin A into the gastrocnemius muscle prior to casting improve toe-walking?
Question type: Intervention
Study design: Randomized controlled
Investigators from the Karolinska Institute in Sweden sought to determine the efficacy of combined cast and botulinum toxin A (BTA) as compared to casting alone for treatment of toe-walking. All children evaluated for idiopathic toe-walking at the authors’ clinic between 2005 and 2010 were eligible for study inclusion. Children were examined by multiple pediatric specialists to exclude other causes of toe-walking, and parents completed a validated …
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