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PICO
Question: Among children born with congenital cytomegalovirus infection, what are the long-term sequelae and neurodevelopmental outcomes?
Question type: Prognosis
Study design: Prospective cohort
Investigators from multiple institutions performed parallel prospective cohort studies to ascertain the long-term sequelae and neurodevelopmental outcomes of congenital cytomegalovirus (cCMV) infection among mother-infant dyads in Malmö, Sweden and London. Live newborns at a single hospital in Malmö and at 3 hospitals in London were tested for CMV between 1977 and 1985 and 1979 to 1986, respectively. CMV testing in Malmö was performed by virus culture of urine within 2 weeks of birth and, in London, by virus culture of throat swabs within 1 week of birth followed by a …
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