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Evidence-based practice is fundamentally about answering patient-centered questions. A pitfall in trying to answer such questions is finding 1 relevant study, appraising it, and making a clinical decision based on that single study. Sometimes a single study is all that exists, but in many cases there are multiple studies that address similar clinical questions. Systematic reviews (SR) and meta-analyses (MA) are frequently used to synthesize large amounts of information from different studies to get an overall assessment of the benefit of a specific treatment, diagnostic tool, or laboratory test, or the overall risk from a specific exposure.
SR and MA are fundamentally different from review articles. A narrative review article is usually written by a content expert and can be an excellent way to get a broad overview of a …
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