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American Academy of Pediatrics
Orthopaedics

Steroids Prevent Scoliosis in Duchenne Muscular Dystrophy

AAP Grand Rounds December 2013, 30 (6) 62; DOI: https://doi.org/10.1542/gr.30-6-62
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Source: Lebel DE, Corston JA, McAdam LC, et al. Glucocorticoid treatment for the prevention of scoliosis in children with Duchenne muscular dystrophy: long-term follow-up. J Bone Joint Surg. 2013; 95( 12): 1057– 1061; doi: 10.2106/JBJS.L.01577OpenUrlCrossRefPubMed

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Question: Among boys with Duchenne muscular dystrophy, does glucocorticoid treatment decrease the long-term incidence and progression of scoliosis?

Question type: Intervention

Study design: Prospective nonrandomized cohort

Investigators from the University of Toronto sought to determine if the long-term use of glucocorticoids in patients with Duchenne muscular dystrophy (DMD) resulted in a decreased incidence and progression of scoliosis and a decreased need for spinal surgery. Boys between ages 7 and 10 years with a diagnosis of DMD who were able to walk were enrolled in the study. The treatment group consisted of study participants whose parents consented to corticosteroid treatment; the control group consisted of boys whose parents elected not to use corticosteroids. …

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AAP Grand Rounds
Vol. 30, Issue 6
1 Dec 2013
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Steroids Prevent Scoliosis in Duchenne Muscular Dystrophy
AAP Grand Rounds Dec 2013, 30 (6) 62; DOI: 10.1542/gr.30-6-62

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Steroids Prevent Scoliosis in Duchenne Muscular Dystrophy
AAP Grand Rounds Dec 2013, 30 (6) 62; DOI: 10.1542/gr.30-6-62
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