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PICO
Question: Among adolescents with idiopathic scoliosis, does wearing a back brace, as compared to observation, slow the progression of scoliosis and help patients avoid surgery?
Question type: Intervention
Study design: Prospective, randomized, controlled, with patient preference arm
Investigators from the University of Iowa and Washington University sought to determine the effect of bracing on curve progression and rate of surgery in adolescents with idiopathic scoliosis. They conducted a multicenter (25 institutions) randomized trial of patients with scoliosis and typical indications for bracing including age, skeletal maturity, and degree of curve (Cobb angle of 20° to 40°). Both a randomized cohort (randomized to bracing or observation) and a preference cohort were enrolled. Patients in the bracing …
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