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PICO
Question: Among children and adolescents with chronic migraine, does cognitive behavioral therapy plus amitriptyline reduce the number of days with migraine compared to headache education plus amitriptyline?
Question type: Intervention
Study design: Randomized clinical trial
Investigators at the Headache Center at Cincinnati Children’s Hospital conducted a randomized clinical trial to compare the efficacy of cognitive behavioral therapy (CBT) combined with amitriptyline to headache education plus amitriptyline for children with chronic migraine headaches. Youth 10 to 17 years old, with at least 15 headaches per month and a Pediatric Migraine Disability Assessment Score (PedMIDAS) >20, were randomized …
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