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PICO
Question: Among children with congenital heart disease who require surgical repair, what is the increased risk of cancer related to cumulative radiation exposure?
Question type: Harm
Study design: Retrospective cohort
Investigators from Duke University conducted a study of children with congenital heart disease (CHD) who required surgery to determine their predicted increased cancer risk given their cumulative exposure to radiation from imaging modalities. Investigators included children ≤6 years of age who had previously undergone 1 of 7 primary surgical procedures for CHD (isolated atrial septal defect [ASD] closure, isolated ventricular septal defect closure, atrioventricular canal defect repair, tetralogy of Fallot …
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