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PICO
Question: Among 5- to 6-year-old liver transplant recipients, what are the longterm cognitive and academic outcomes?
Question type: Prognosis
Study design: Prospective multicenter cohort
Investigators from the Functional Outcomes Group (FOG), which includes 20 pediatric liver transplant centers in the Studies of Pediatric Liver Transplantation (SPLIT) collaborative, sought to determine the evolution of cognitive and academic deficits in children after liver transplant. Study children were identified and recruited through the SPLIT registry, and were 5–6 years of age when enrolled and ≥2 years posttransplant. Cognitive performance was measured at enrollment (Time 1) and repeated when participants were 7–9 years old (Time 2). Patients were tested …
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