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PICO
Question: Among children 0–17 years of age with severe traumatic brain injury (TBI), does adherence to the 2003 Pediatric TBI Guidelines improve survival or neurological outcome?
Question type: Prognosis
Study design: Retrospective cohort
Investigators from multiple US medical centers assessed the effect of compliance with the 2003 Pediatric Traumatic Brain Injury (TBI) Guidelines1 on patient outcome. They evaluated data from children (aged 0–17 years) treated for severe TBI (defined as a postresuscitation Glasgow Coma Scale ≥8, an abnormal initial head CT, and an abbreviated head injury severity score ≤3) at 5 geographically dispersed pediatric ICUs participating in the Pediatric Neurocritical Care Research Group.2 To be included in the study, the child must have survived at least 48 hours after injury …
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