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PICO
Question: Among children with obstructive sleep apnea syndrome aged 5.0–9.9 years, does treatment with adenotonsillectomy compared to watchful waiting result in increased weight gain?
Question type: Intervention
Study design: Randomized controlled
Investigators from multiple institutions conducted the Childhood Adenotonsillectomy Trial (CHAT) to determine if children with obstructive sleep apnea syndrome (OSAS) have increased weight gain after adenotonsillectomy (AT). This multicenter, single-blind, randomized controlled trial included children, 5.0–9.9 years old, with symptoms or signs of sleep-disordered breathing who were recruited from general pediatric, sleep, and otolaryngology clinics. Participants diagnosed with mild to moderate OSAS on enrollment polysomnography were randomized to undergo AT versus watchful waiting with supportive care, followed in 7 months by repeat polysomnography and growth …
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