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Question: Among children with acute lymphoblastic leukemia, is being overweight or obese associated with minimal residual disease after induction chemotherapy or poorer event-free survival?
Question type: Descriptive
Study design: Retrospective cohort
Investigators from Children’s Hospital Los Angeles (CHLA) evaluated the associations between body mass index (BMI) of children with leukemia and (1) persistence of leukemia after 1 month of chemotherapy, and (2) eventfree survival (EFS). Study participants included children aged 1–21 years with newly diagnosed B-precursor acute lymphoblastic leukemia (BP-ALL) followed at CHLA between 2008 and 2013 and treated according to standard protocol. Demographic and clinical …
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