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PICO
Question: Among pregnant women with a singleton gestation resulting in a live birth, is low-to-moderate prenatal alcohol exposure associated with selected adverse birth outcomes compared to women who did not drink alcohol during pregnancy?
Question type: Harm/Causation
Study design: Prospective cohort
Researchers at Yale and Brown Universities conducted a prospective cohort study to investigate alcohol consumption during pregnancy and the risks of intrauterine growth retardation (IUGR), low birth weight, reduced head circumference, preterm delivery, and selected congenital malformations.
The study population consisted of pregnant women with singleton gestations resulting in a live birth who were enrolled in 2 related prospective longitudinal cohort studies (1996–2000). All women completed a …
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