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PICO
Question: Among children followed to 7–9 years of age, does prenatal exposure to polycyclic aromatic hydrocarbons result in decreased development of brain white matter and behavioral changes?
Question type: Harm/causation
Study design: Prospective cohort
Investigators from Los Angeles and New York City conducted a prospective cohort study to assess the effects of prenatal exposure to air pollutants, specifically polycyclic aromatic hydrocarbons (PAH), on subsequent neurocognitive development and brain structure in later childhood. Study participants were selected children born to a group of 665 mothers who carried backpacks with personal monitors to measure PAH exposure over a …
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