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Question: Among invasive Neisseria meningitidis isolates in the United States, have the serogroup distribution and molecular characteristics changed following licensure of quadrivalent meningococcal conjugate vaccines?
Question type: Descriptive
Study design: Retrospective cohort
Investigators from 10 states and the Centers for Disease Control and Prevention (CDC) conducted a retrospective study to assess changes in the population structure of Neisseria meningitidis isolates following licensure of 2 quadrivalent meningococcal conjugate vaccines for use in adolescents that protect against disease caused by serogroups A, C, W, and Y (MenACWY). Study data were abstracted from the CDC’s Active Bacterial Core surveillance (ABCs) network, a population- and …
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