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PICO
Question: Among survivors of childhood cancer, what are the characteristics and predictors of late pulmonary dysfunction compared to healthy controls?
Question type: Prognosis
Study design: Prospective cohort
Investigators from the City of Hope National Medical Center, Duarte, CA, and the University of Alabama, Birmingham, assessed the degree of pulmonary dysfunction among childhood cancer survivors compared to age- and sex-matched healthy controls. Participants included survivors who had a cancer diagnosis at age <22 years and who had completed cancer treatment ≥2 years prior to enrollment. Age- and sex-matched controls were recruited from the general population. Medical records of cancer survivors were reviewed for …
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