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PICO
Question: Among infants with prenatal exposure to second-hand tobacco smoke, are there measureable differences in neurodevelopmental outcomes at 18 months of age compared to outcomes from children without this exposure?
Question type: Harm/causation
Study design: Prospective cohort
Investigators from multiple international sites conducted a prospective cohort study to assess the effects of prenatal exposure to second-hand smoke (SHS) in Greek mothers on neurodevelopment in their offspring at 18 months of age. Study participants included nonsmoking mothers with healthy singleton pregnancies who had full information on smoking habits …
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