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PICO
Question: Among children and young adults who are penicillin-allergic, what are the incidence of adverse effects and the type of allergic reactions when using cephalosporins and other antibiotics for surgical prophylaxis?
Question type: Descriptive
Study design: Retrospective cohort
Investigators from Ohio and Canada determined the incidence of adverse effects from antibiotic administration for surgical prophylaxis in patients with a documented penicillin allergy. Patients were eligible if they were penicillin-allergic and required intraoperative administration of antibiotics for surgical prophylaxis at Nationwide Children’s Hospital, Columbus, OH, from 2010–2012. The patient’s electronic medical record was used to ascertain age, penicillin allergy, type of past allergic reaction to …
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