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American Academy of Pediatrics
Hospital Medicine

Oxygen Saturation Targets in Infants With Bronchiolitis

AAP Grand Rounds December 2015, 34 (6) 64; DOI: https://doi.org/10.1542/gr.34-6-64
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Cunningham S, Rodriguez A, Adams T, et al. Oxygen saturation targets in infants with bronchiolitis (BIDS): a double-blind, randomised, equivalence trial. Lancet. 2015; 386( 9998): 1041– 1048; doi: 10.1016/S0140-6736(15)00163-4OpenUrlCrossRefPubMed

Key words
  • bronchiolitis
  • oxygen saturation target

PICO

Question: Among infants hospitalized with bronchiolitis, is a minimum oxygen saturation target of 90% versus 94% associated with equivalent outcomes?

Question type: Intervention

Study design: Randomized controlled

Investigators from multiple institutions in the United Kingdom conducted a randomized controlled trial to determine if outcomes were equivalent for infants hospitalized with bronchiolitis using an oxygen saturation (SpO2) target of ≥90% compared to ≥94%. For the study, previously healthy infants from 6 weeks to 12 months of age hospitalized with acute viral bronchiolitis were randomized to monitoring with standard or modified pulse oximeters. Parents and health care providers were blinded as to study infants’ group allocation. With the modified oximeters, oxygen saturations between 85% and 100% were artificially skewed upwards, so that an actual …

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AAP Grand Rounds
Vol. 34, Issue 6
1 Dec 2015
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Oxygen Saturation Targets in Infants With Bronchiolitis
AAP Grand Rounds Dec 2015, 34 (6) 64; DOI: 10.1542/gr.34-6-64

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Oxygen Saturation Targets in Infants With Bronchiolitis
AAP Grand Rounds Dec 2015, 34 (6) 64; DOI: 10.1542/gr.34-6-64
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