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PICO
Question: Among US children with pneumococcal meningitis, how has the epidemiology changed following the introduction of the 13-valent pneumococcal conjugate vaccine?
Question type: Descriptive
Study design: Case series
Investigators from 8 US children’s hospitals who were part of the US Pediatric Multicenter Pneumococcal Surveillance Study Group conducted a study to assess changes in the epidemiology of pneumococcal meningitis (PM) after the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) in 2010. For the study, data on patients ≤18 years of age with PM between 2007 and 2013 were abstracted from the group’s database. PM was defined as a Streptococcus pneumoniae-positive cerebrospinal fluid (CSF) …
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