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PICO
Question: Among reproductive age women, what is the association between lactation duration and atherosclerosis in midlife?
Question type: Causation
Study design: Prospective cohort
Investigators from multiple institutions studied the effect of lactation duration on atherosclerosis in women during midlife using data from The Coronary Artery Risk Development in Young Adults (CARDYA) study, a multicenter prospective cohort of 2,787 18- to 30-year-old women enrolled in 1985–1986. Inclusion criteria included CARDYA participants who (1) did not have heart disease or diabetes at enrollment, (2) gave birth at least once after enrollment, (3) reported lactation duration, and (4) had atherosclerosis measurement data at 20-year follow-up. The primary independent …
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