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American Academy of Pediatrics
Neonatal-Perinatal Medicine

Neonatal Hypoglycemia – How Low Can We Go?

AAP Grand Rounds January 2016, 35 (1) 1-3; DOI: https://doi.org/10.1542/gr.35-1-1
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McKinlay CJD, Alsweiler JM, Ansell JM, et al. Neonatal glycemia and neurodevelopmental outcomes at 2 years? N Engl J Med. 2015; 373( 16) 1507– 1518; doi: 10.1056/NEJMoa1504909OpenUrlCrossRefPubMed

Key words
  • newborn
  • hypoglycemia
  • neurologic outcome

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Question: Among neonates of >35 weeks’ gestation at risk for hypoglycemia, do the duration, frequency, and severity of low glucose concentrations affect neurodevelopmental outcomes at age 2 years?

Question type: Prognosis

Study design: Prospective cohort

Investigators from New Zealand and Canada prospectively followed a cohort of infants at risk for hypoglycemia to determine the relationship between the duration, frequency, and severity of low glucose concentrations in the early neonatal period and neurodevelopmental outcomes at age 2 years. Newborns enrolled in the study had at least 1 of the following risk factors for hypoglycemia: maternal diabetes, a gestational age <37 weeks, or birth weight that was either <10th or >90th percentile.

Participants underwent intermittent glucose sampling for the first 24–48 hours of life, or …

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AAP Grand Rounds
Vol. 35, Issue 1
1 Jan 2016
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Neonatal Hypoglycemia – How Low Can We Go?
AAP Grand Rounds Jan 2016, 35 (1) 1-3; DOI: 10.1542/gr.35-1-1

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Neonatal Hypoglycemia – How Low Can We Go?
AAP Grand Rounds Jan 2016, 35 (1) 1-3; DOI: 10.1542/gr.35-1-1
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