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PICO
Question: Among children with acute lung injury, do corticosteroids affect survival or duration of mechanical ventilation?
Question type: Treatment
Study design: Prospective cohort
Investigators from Children’s Hospital of Philadelphia assessed the association between corticosteroid exposure and outcomes in children with acute respiratory distress syndrome (ARDS). They prospectively screened patients admitted to the PICU between 2011 and 2014. Children 1 month to 18 years of age who were mechanically ventilated for >1 day and met the criteria for acute lung injury (PaO2/FiO2 ≤300 and bilateral parenchymal infiltrates) were enrolled. Children with …
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