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PICO
Question: Among breastfed infants, does the introduction of allergenic foods at 3 months of age protect against the development of food allergy as compared to those who exclusively breastfeed until approximately 6 months of age?
Question type: Intervention
Study design: Randomized controlled
Investigators from multiple institutions in the United Kingdom evaluated the impact of early introduction of allergenic foods on the development of food allergy in breastfed infants. Infants who were 3 months of age and exclusively breastfed were recruited from the general population and randomly assigned to 1 of 2 groups: an early introduction group (EIG), in which parents were instructed to feed their infant 2 g of 6 allergenic foods twice weekly (starting with cow’s milk, followed in random order by peanut, egg, sesame, …
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