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PICO
Question: Among children who survived out-of-hospital cardiac arrest and were comatose after arrest, what are the neurobehavioral outcomes 12 months following the event?
Question type: Prognosis
Study design: Prospective cohort
Investigators from multiple institutions sought to determine the neurobehavioral outcomes 12 months following out-of-hospital cardiac arrest (OH-CA) among children who were comatose following resuscitation. Participants in the current study consisted of a subgroup of children who had been enrolled in a clinical trial, Therapeutic Hypothermia After Pediatric Cardiac Arrest, Out-Of-Hospital (THAPCA-OH), to determine whether targeted temperature management to hypothermia (33.0°C) was more beneficial than targeting to normothermia (36.8°C). Neurobehavioral function …
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