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Researchers from the Kaiser Permanente (KP) Vaccine Study Center, Oakland, CA, conducted a retrospective cohort study to determine the effectiveness of tetanus-diphtheria–acellular pertussis (Tdap) vaccination of pregnant women in protecting their infants against pertussis. For the study, medical record data on infants born at KP Northern California hospitals from 2010 to 2015 were reviewed; only infants born at >37 weeks’ gestation were included. Vaccine information on mothers of study participants was also abstracted from KP medical records. Mothers were classified as receiving Tdap during pregnancy (>7 days prior to delivery) or not receiving a dose of vaccine during pregnancy. Data on maternal Tdap immunization prior to pregnancy (within 2 years) or after pregnancy (after birth of the study participant) were also collected. Study participants were …
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