Increasing Incidence of Celiac Disease

Investigators from the Mayo Clinic conducted a retrospective study to determine population-based trends in the incidence and prevalence of celiac disease (CD) in children ≤18 years old. For the study, the investigators used data collected as part of the Rochester Epidemiology Project and information from previous studies to identify cases of CD among children residing in Olmstead County, Minnesota from 1994 to 2014. Medical record data of identified children with CD were reviewed, and information on demographics, clinical presentation, small bowel biopsy results, CD-specific antibody tests, and anthropometric measurements abstracted. Patients were included if biopsy results confirmed a diagnosis of CD. If no biopsy was performed, cases were confirmed if clinical presentation and positive serologic tests …