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Investigators from multiple institutions conducted an observational study to assess the effectiveness of a third dose of MMR in the control of a mumps outbreak. The mumps outbreak occurred at the University of Iowa from August 2015–May 2016. The University of Iowa requires all students upon enrollment to submit provider-signed vaccination records with verification of the dates of receipt of 2 doses of MMR. During the mumps outbreak, a vaccination campaign was launched in which a third dose of MMR was offered to students 18–24 years old.
Study participants were students enrolled at the university for the 2015–2016 academic year. The primary exposure was vaccination dose status, categorized as 0, 2, or 3 doses as determined by review of …
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