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Investigators from multiple institutions conducted a cross-sectional study to assess the association between coronary artery disease risk factors and carotid intima-media thickness in children. Participants were fifth graders attending schools in southern Maine. For the study, families of participating children completed a questionnaire regarding history of early coronary vascular disease (CVD) in either parents or grandparents, and average physical activity in the child. The following data were collected on each study participant: height and weight (to calculate BMI), blood pressure (BP), total cholesterol, high-density lipoprotein cholesterol (HDL-C), and fasting glucose. Cut-off values were established to determine the presence of a coronary artery disease risk factor, including family history of early CVD (occurring at <55 years in male …
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