Prognosis of Childhood Epilepsy

Investigators from multiple institutions analyzed data from the Norwegian Mother and Child Cohort Study (MoBa) to assess shortterm seizure outcomes in children with epilepsy (CWE). MoBa is a nationwide cohort study of children born in Norway between 1999 and 2009. For the current study, the authors reviewed data from the Epilepsy in Young Children Study, which was embedded in MoBa. CWE were identified through linkage with the Norwegian Patient Registry and parental reports in periodic questionnaires; medical record review and parental interviews were used to capture clinical information about seizures and treatments. Only children with at least 1 year of follow-up were included in the analyses. The primary study outcome was drug-resistant epilepsy (DRE), defined as seizures within the last year of patient follow-up despite trials of at least 2 antiepileptic drugs. Participants without …