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American Academy of Pediatrics
General Pediatrics

Exposure to General Anesthesia and Early Childhood Development

AAP Grand Rounds March 2019, 41 (3) 31; DOI: https://doi.org/10.1542/gr.41-3-31
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Source: O’Leary JD, Janus M, Duku E, et al. Influence of surgical procedures and general anesthesia on child development before primary school entry among matched sibling pairs. JAMA Pediatr. 2018 5 November [published online ahead of print]; doi: 10.1001/jamapediatrics.2018.3662OpenUrlCrossRef

Investigators from multiple Canadian institutions conducted a retrospective sibling-matched cohort study to assess the effect of surgical procedures requiring general anesthesia on early childhood development. Data were obtained from the Institute for Clinical Evaluative Sciences (ICES) in Toronto. ICES houses demographic and child development information for all children enrolled in Ontario public and Catholic schools from 2004–2012. Child development information was obtained through administration of the Early Development Instrument (EDI), a 103-item questionnaire completed by teachers before student kindergarten entry (child age of 5–6 years); it contains 5 major domains (physical health and well-being, social knowledge and competence, emotional health and maturity, language and cognitive development, and communication …

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AAP Grand Rounds
Vol. 41, Issue 3
1 Mar 2019
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Exposure to General Anesthesia and Early Childhood Development
AAP Grand Rounds Mar 2019, 41 (3) 31; DOI: 10.1542/gr.41-3-31

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Exposure to General Anesthesia and Early Childhood Development
AAP Grand Rounds Mar 2019, 41 (3) 31; DOI: 10.1542/gr.41-3-31
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