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American Academy of Pediatrics
Infectious Diseases

Central Nervous System Disease and Adenoviruses

AAP Grand Rounds March 2019, 41 (3) 35; DOI: https://doi.org/10.1542/gr.41-3-35
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Source: Schwartz KL, Richardson SE, MacGregor D, et al. Adenovirus-associated central nervous system disease in children. J Pediatr. 2018 6 November [published online ahead of print]; doi: 10.1016/j.jpeds.2018.09.036OpenUrlCrossRef

Investigators from The Hospital for Sick Children (SickKids) in Toronto conducted a retrospective observational study to characterize adenovirus-associated central nervous system (CNS) disease in children. Three data sources were used: the SickKids microbiology and encephalitis databases (which include children who had been admitted to SickKids during 2000–2016 and 1996–2016, respectively) and a literature search. Children in the SickKids databases were eligible for the study if they were previously healthy; were 1 month to 18 years old; had neurologic symptoms; did not have a preexisting neurologic disorder; and had adenovirus detected by direct fluorescent antibody staining, culture, or polymerase chain reaction (PCR). Child cases identified from the literature search were eligible if they had a neurologic diagnosis other than febrile seizures …

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AAP Grand Rounds
Vol. 41, Issue 3
1 Mar 2019
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Central Nervous System Disease and Adenoviruses
AAP Grand Rounds Mar 2019, 41 (3) 35; DOI: 10.1542/gr.41-3-35

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Central Nervous System Disease and Adenoviruses
AAP Grand Rounds Mar 2019, 41 (3) 35; DOI: 10.1542/gr.41-3-35
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