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Investigators from Kansai Medical University, Osaka, Japan, conducted a prospective study to assess the impact of excessive sodium intake on the efficacy of treatment with 1-desamino-8-D-arginine vasopressin (DDAVP) therapy in children with nocturnal enuresis. Children, 7 to 10 years old, who were seen at Kansai Medical University Hospital with monosymptomatic nocturnal enuresis were enrolled in the study. A morning urine sample was collected from participants, and urinary sodium and creatinine levels were measured. The values for urinary sodium and creatinine levels in the spot urine specimens were used to estimate daily sodium intake by using a previously published equation.1 Children were classified as having appropriate or excessive sodium intake based on guidelines from the Japanese Ministry of Health, Labour and Welfare; recommended daily sodium …
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