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Investigators from multiple institutions conducted a prospective cohort study to describe the epidemiology of lower respiratory infections in children with cystic fibrosis (CF). Patients were eligible if they were diagnosed with CF after newborn screening and were participating in the Australian Respiratory Early Surveillance Team for CF program at 2 Australian hospitals between 2000–2018. Participants received a bronchoscopy with bronchoalveolar lavage (BAL) at 3 months, 12 months, and annually until age 6. BAL was collected in the right middle lobe and lingula and sent for culture. Clinical management of participants’ CF followed international guidelines, including routine …
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