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Investigators from multiple Korean institutions conducted a retrospective cohort study to identify risk factors for and outcomes with extended-spectrum β-lactamase (ESBL) UTIs among children. Children ≤24 months of age who presented to the study hospital between 2010 and 2016 and received a diagnosis of a febrile UTI caused by gram-negative bacteria were eligible. Febrile UTI was defined as fever, pyuria, and a single pathogen titer of >50,000 colony-forming units per milliliter obtained via urinary catheterization. Child demographic and clinical characteristics (eg, presence of underlying disease such as urinary tract abnormalities, history of hospitalization or UTI, antibiotic use within previous 3 months, and technetium 99m dimercaptosuccinic acid [DMSA] scan results) were obtained from the medical …
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