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Investigators from the University of Texas Health Sciences Center San Antonio and Texas Children’s Hospital, Houston, conducted a systematic review to characterize the demographics, presenting symptoms, laboratory findings, and outcomes in children diagnosed with COVID-19 and identify specific presenting symptoms and laboratory findings in those who developed multisystem inflammatory syndrome in children (MIS-C). The authors used a systematic process to identify relevant studies for inclusion. Data from studies of children and young adults from 0 to 21 years old with COVID-19, confirmed by PCR testing, were extracted. Patients were classified as developing MIS-C based on the CDC definition. Presenting symptoms and initial laboratory results were compared in children with …
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