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Investigators from the Netherlands conducted a prospective observational study to assess immunogenicity of routine immunizations among preterm infants. Study participants were infants born at <36 weeks’ gestation enrolled at one of 8 Dutch hospitals between 2015 and 2017. Following the Dutch vaccination schedule, participants received a combination vaccine containing diphtheria and tetanus toxoids, acellular pertussis, inactivated poliomyelitis, Haemophilus influenzae type b (Hib), and hepatitis B (DTP-IPV-Hib-HBV; Infanrix-hexa, GlaxoSmithKline). It was administered at 6-9 weeks and 3 and 4 months of age as a primary series with a booster at 11 months of age, and a 10-valent pneumococcal conjugate vaccine (PCV10; Synflorix, GlaxoSmithKline) was administered at 6-9 weeks and 4 months as a primary series with a booster dose …
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