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Investigators from Jikei University School of Medicine, Tokyo, Japan, conducted a randomized controlled trial (RCT) to assess the association between supplementation of breastfeeding in newborns with cow’s milk formula (CMF) or breastfeeding with or without supplementation with an amino acid-based elemental formula (EE) and development of asthma among children at risk for atopy. The current study was a continuation of an RCT to assess the association of atopy and CMF supplementation. For the previous study, breastfed newborns with at least 1 family member (father, mother, sibling) with a history of atopic disease were randomized to receive small amounts of CMF or EE as needed to supplement breastfeeding …
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